Sleep Deeper, Recover Smarter: How to Hack Your Circadian Rhythm

Dr. Sandra Handlbauer-Zrust, Registered Nutritional Therapist and Certified Functional Medicine Practitioner

Sleep Deeper, Recover Smarter: How to Hack Your Circadian Rhythm

 

Why Sleep Is Our Most Important Biohacking Tool

Sleep is far more than just “doing nothing” – it is our most natural regeneration tool and ranks among the most effective biohacks. During the night, highly complex processes take place in the body: cells regenerate, the immune system is strengthened, the brain processes impressions and consolidates memories. At the same time, hormones such as growth hormone are released, cortisol levels drop with healthy circadian rhythms, and metabolism is regulated. All of this supports essential physiological repair and recovery processes.

The individual sleep stages are particularly fascinating:

🥱 Falling asleep phase (Stage 1): The transition from wakefulness to sleep. Here, pulse and breathing slow down, and the brain begins to show alpha and theta wave patterns. Many people experience brief muscle twitches or the sensation of falling during this phase.

😴 Light sleep phase (Stage 2): This stage accounts for about 50% of total sleep time. Body temperature drops, heart rate and breathing slow further. The brain shows so-called "sleep spindles" and K-complexes, which serve as protection mechanisms against external stimuli.

🛌 Deep sleep (Stage 3): This is when the deepest physical regeneration occurs. The brain produces delta waves, the immune system is particularly active, and growth hormones are released. Cell repair, muscle growth, and energy replenishment are especially intense here.

💭 REM sleep (Rapid Eye Movement): Brain activity rises sharply, dreams occur, and emotional and cognitive experiences are processed. This phase is essential for learning, memory, and emotional balance.

The body goes through these sleep cycles about 4–6 times per night. A disrupted sequence – such as from frequent waking, nighttime stress, or poor sleep hygiene – can significantly impair regeneration.

What Is the Circadian Rhythm?

Our circadian rhythm is also known as our “internal clock.” It regulates nearly every function in our body: sleep, energy levels, hormone secretion, digestion, and cell repair. Light is the most powerful time cue ("Zeitgeber" = external synchronizer).

A classic example of a disruption of this rhythm is jet lag: After a long-haul flight to a different time zone, people often feel tired or overstimulated at the "wrong" time, because the body is still stuck in the old day-night cycle.

In my work with clients, I repeatedly see the same disruptive factors throwing the circadian rhythm off balance:

📱 Constant light pollution, especially from artificial blue light in the evening, can impair natural melatonin production.

🍔 Irregular eating and sleeping times disturb the internal clock.

😵 Chronic stress often comes with persistently elevated cortisol levels, which can negatively impact sleep quality and recovery.

Thinking Regeneration Holistically: The Functional Approach

Functional medicine doesn’t see sleep problems as isolated issues, but as signs of an imbalance in the body – for example, due to stress, nutrient deficiencies, or hormonal imbalances. It doesn’t just ask about the symptom but looks for the causes. The goal is to sustainably strengthen the body's ability to regenerate – for more energy, focus, and resilience in everyday life.

This approach can be particularly effective in the area of regeneration and sleep: Strengthening biological rhythms, the nervous system, and micronutrient balance lays the foundation for long-term performance, emotional stability, and a robust immune system – closely linked with hormonal balance, inflammation regulation, and mental load. Instead of merely treating symptoms like fatigue or trouble falling asleep, it asks: Which bodily processes are out of balance? How can I naturally and holistically support my regeneration?

This Is How Your Body Supports Regeneration

Recovery is not a matter of luck, but the result of targeted biological processes – and how well we support these processes determines our ability to regenerate. Besides sufficient sleep, one thing is especially crucial: internal stability. This arises from a balanced biorhythm, a stable nervous system, and adequate cellular energy supply.

A key hormone for regeneration is melatonin, which is produced in the pineal gland region of the brain. Its release follows the course of daylight – peaking at night between 2 and 4 a.m. For this rhythm to function smoothly, the body needs sufficient daylight, regular bedtimes, a quiet sleeping environment, and optimal nutrient availability.

The parasympathetic nervous system also plays a crucial role: It is responsible for "rest and digest," i.e., recovery, digestion, and cell repair. If this system is constantly overrun by stress and overstimulation, the body can no longer effectively switch into recovery mode.

A healthy rhythm, combined with conscious moments of relaxation, regular exercise, and targeted micronutrient management, forms the foundation for true regeneration. Because only those who recover can remain productive, resilient, and healthy in the long run.

Micronutrients: Silent Helpers for Sleep and Recovery

A balanced supply of certain micronutrients and amino acids is crucial for healthy sleep and nighttime recovery. The following six key nutrients play a central role in the nervous system, hormone balance, and energy production.

1. Magnesium – The Natural Relaxation Aid
Magnesium is involved in over 300 enzymatic reactions and plays a key role in regulating the nervous system. It supports the function of the calming neurotransmitter GABA, thereby promoting sleep onset and quality. Magnesium deficiency can lead to nervousness, muscle tension, and sleep disorders. (1)

2. Vitamin B6, B12, and Folate – For Mental Balance and Sleep Quality
These B vitamins are essential for the formation of neurotransmitters like serotonin and GABA, which significantly influence the sleep-wake cycle. A deficiency may manifest as mood swings, fatigue, or insomnia. Studies show positive effects of targeted B6 supplementation on stress perception and sleep onset. (2)

3. Zinc – Supports Cognitive Functions and Sleep Regulation
Zinc is a trace element that regulates the activity of over 300 enzymes. It plays a major role in cognitive processes, hormone regulation, and neuronal communication. A deficiency can impair sleep quality, alter stimulus processing, and promote inflammation. (3)

4. Vitamin D – For Immune Balance and Sleep Quality
Vitamin D is not only important for bone health and the immune system but also influences sleep architecture. It’s involved in melatonin synthesis and regulates inflammatory processes that can disrupt sleep. Supplementation in deficiency states can improve sleep onset and efficiency. (4)

5. Coenzyme Q10 – Energy for the Cells
Coenzyme Q10 (CoQ10) is a central component of mitochondrial energy production, ensuring that our cells – especially in the brain, heart, and muscles – have enough energy. During times of high stress or with aging, supplementation can help reduce fatigue and promote recovery. (5)

6. L-Tryptophan – Precursor of Serotonin and Melatonin
L-Tryptophan is an essential amino acid and the direct precursor of serotonin, which is then converted into melatonin – the key hormone for a stable day-night rhythm. Studies show that increased tryptophan intake improves sleep duration, quality, and emotional balance. (6)

BIOGENA ONE as a Daily Micronutrient Booster for Better Sleep & Recovery

BIOGENA ONE provides an intelligent combination of micronutrients that support important physiological processes related to sleep and recovery. With just one convenient stick per day, comprehensive support is made easy – simple and ideal for daily routines. Especially during stressful times or with irregular eating habits, this simplicity can be key to staying consistent and giving the body everything it needs.

Stress Resilience & Cortisol Regulation:

  • ✅ Magnesium contributes to normal nervous system function
  • ✅ Vitamins B6, B12 & folate support psychological function*

Sleep Quality & Melatonin Synthesis:

  • ✅ Magnesium, zinc, and vitamin B6 are involved in the synthesis of neurotransmitters like GABA and melatonin
  • ✅ Amino acids like glycine promote nighttime relaxation
  • ✅ L-tryptophan precursors + cofactors support serotonin and melatonin production

Cellular Regeneration:

  • ✅ Vitamins C, E, selenium, and zinc help protect cells from oxidative stress*
  • ✅ KANEKA Ubiquinol™ (CoQ10) provides energy at the mitochondrial level

(*according to Regulation (EU) No. 432/2012)

Especially because exhaustion, sleep disorders, and reduced performance are often linked to silent micronutrient deficiencies, BIOGENA ONE represents the "missing link" for many people – the foundation for more energy, mental clarity, and sustainable recovery.

BIOGENA ONE Illustration

Practical Tips for Deeper Sleep

In my consultations, I repeatedly observe that it’s not the duration of sleep that’s lacking, but the everyday habits that either promote or disturb sleep. That’s why it’s important to me to give my clients simple, actionable levers they can implement immediately. The following four categories have proven especially effective:

🥦 Nutrition:

Many underestimate how significantly our diet influences sleep quality. A stable blood sugar level, the availability of certain amino acids, and an anti-inflammatory diet measurably affect relaxation and sleep.

  • Magnesium-rich foods like leafy greens, nuts, and seeds should be integrated into daily life.
  • Tryptophan-rich foods such as turkey, oats, and bananas promote serotonin production.
  • Prefer easily digestible meals in the evening.
  • Avoid caffeine and alcohol in the evening.
  • A soothing tea made from lemon balm or lavender can have a calming effect.
  • Have your last meal 2–3 hours before bedtime.
  • Regular meal times support the natural sleep-wake cycle.

🏃 Physical Activity:

Exercise not only reduces stress but also supports a healthy sleep-wake rhythm.

  • Regular daily physical activity – ideally outdoors – improves sleep quality.
  • Avoid intense training right before going to bed.
  • Gentle evening walks or light stretching can help you unwind.

🧠 Mental Balance:

An overstimulated mind can significantly disrupt sleep – that's why mental relaxation is important.

  • Establish evening rituals like reading, journaling, or meditation.
  • Reduce screen time before sleep or use blue light filters.
  • Breathing techniques or progressive muscle relaxation help to switch off.

🛏️ Sleep Environment:

A sleep-promoting environment is essential for restful sleep.

  • Darkness, silence, and a comfortable room temperature support falling and staying asleep.
  • Ban electronic devices from the bedroom.
  • Choose a comfortable bed and a suitable mattress.
  • Maintain a regular sleep rhythm: go to bed and wake up at the same time whenever possible.

In my experience, those who get enough movement during the day fall asleep faster and sleep more deeply. Physical activity helps reduce stress and strengthens the natural day-night rhythm.

  • Get daily light exposure and moderate exercise in the morning (e.g., a 20-minute walk).
  • Regular physical activity promotes healthy sleep.
  • Intense workouts should be finished 4–5 hours before bedtime.

🛌 Sleep Hygiene:

Often, small changes in the environment are enough to noticeably improve sleep. I recommend that my clients treat their bedroom as a sanctuary.

  • Reduce blue light sources in the evening (e.g., screen filters, warm light sources).
  • Darken, cool, and quiet the bedroom.

🌙 Evening Routine:

A fixed evening routine signals to the body: it’s time to wind down. Just a few minutes of conscious relaxation can make a difference.

  • Turn off digital devices 60 minutes before bedtime.
  • Breathing exercises, meditation, or reading help to relax.
  • A fixed bedtime supports your natural rhythm.
  • Establish fixed sleep times, even on weekends.
  • Relaxing rituals like meditation, reading, or a warm shower promote winding down.

Integrating these simple but effective measures can improve your sleep quality and stabilize your circadian rhythm.

My Conclusion

Better sleep doesn’t necessarily mean more sleep, but smarter sleep. Small adjustments – from morning daylight to targeted micronutrient support – can have a big impact on energy, mental clarity, and recovery.

If you often feel like you're running on low power during the day, it’s worth taking an honest look at your sleep quality. How often do you wake up refreshed? Which evening habits benefit you – and which ones unknowingly drain your energy? This is where smarter sleep begins: with small, conscious decisions you can make every day.

Start with a realistic goal: for example, stabilize your bedtime by 15 minutes, reduce screen time in the evening, or establish a relaxing routine. Tools like BIOGENA ONE can help holistically support your body, especially during times of high stress.

Take the first step today – your body will thank you with more energy, focus, and inner stability.

References

  1. de Baaij, J.H.F., et al. (2015). Magnesium in Man: Implications for Health and Disease. Physiol Rev. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024559/
  2. Bottiglieri, T., et al. (2016). Vitamin B12, folate, and neuropsychiatric disorders. Nutr Rev. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/
  1. DiNicolantonio, J.J., et al. (2018). Zinc deficiency as a possible risk factor for Alzheimer’s disease and depression: A review. J Alzheimers Dis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713303/
  2. Muscogiuri, G., et al. (2019). The role of vitamin D in sleep disorders: a systematic review and meta-analysis. Nutrients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912284/
  3. Saini, R. (2024). Coenzyme Q10 in chronic fatigue and sleep dysfunction: A review. J Clin Sleep Med. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10779395/
  4. Jenkins, T.A., et al. (2016). Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728667/
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