More energy that lasts
When your gut helps your body perform
Butyrate as your body’s natural energy driver
In the BIOGENA ONE study, butyrate-producing bacteria increased by 77 %. These microorganisms create short-chain fatty acids that serve as direct fuel for intestinal cells and stabilize energy metabolism. A stronger gut lining means better nutrient uptake and less low-grade inflammation, one of the main reasons for fatigue and poor recovery. When your microbiome produces more butyrate, your body generates steady energy and greater endurance throughout the day.
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Calm focus from the inside
A balanced gut supports mental balance
Lactobacillus and the gut-brain connection
The study recorded a 91 % increase in Lactobacillus species, bacteria that interact directly with the gut-brain axis. They support serotonin balance, influence cortisol levels, and modulate inflammatory signals that affect clarity and focus. By strengthening this biological link, ONE helps your body respond more calmly to stress and sustain mental performance even during long, demanding days.
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Lightness starts in your gut
Noticeable comfort in just four weeks

Bifidobacteria for smoother digestion
Participants in the 4-week study reported measurable relief of digestive discomfort, supported by a 191 % increase in Bifidobacterium species. These bacteria maintain a stable intestinal environment, help convert fiber into nutrients, and keep harmful microbes in check. A microbiome rich in Bifidobacteria means less bloating, smoother digestion, and a lighter feeling after every meal.
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Proven results you can trust
Measurable change backed by real data
Four weeks that made a difference
The BIOGENA ONE study observed 16 participants over four weeks using validated questionnaires and microbiome sequencing. All data showed clear biological improvements – higher levels of beneficial bacteria, better digestive scores, and a healthier gut environment. These measurable shifts confirm what users report: ONE creates visible, data-driven change inside the body that you can feel in everyday life.
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Inside ONE: Proven by a Clinical Study
In a 4-week clinical study, BIOGENA ONE was shown to influence both subjective well-being and measurable microbiome markers.

Butyrate as your body’s natural energy driver
In the BIOGENA ONE study, butyrate-producing bacteria increased by 77 %. These microorganisms create short-chain fatty acids that serve as direct fuel for intestinal cells and stabilize energy metabolism. A stronger gut lining means better nutrient uptake and less low-grade inflammation, one of the main reasons for fatigue and poor recovery. When your microbiome produces more butyrate, your body generates steady energy and greater endurance throughout the day.
Try ONE today

A study confirms it - BIOGENA ONE works
Following the first in-house microbiome study, a second eight-week clinical study again showed clear and measurable results. Participants experienced significant improvements in energy, digestion, sleep quality and emotional wellbeing.
86%
more energy
77%
felt less stressed
63%
experienced better sleep
77%
reported better digestion
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Free from everything your body doesn’t need
BIOGENA ONE stands for uncompromising quality, developed without unnecessary additives, allergens or fillers.
No Added Sugar
Naturally clean in taste and completely free from artificial sweeteners or hidden sugars
No Gluten
Formulated to be 100 percent gluten free for optimal tolerance and lightness in everyday life
No Milk
Free from milk and lactose to support gentle digestion and suitability for sensitive individuals
No Nuts
Safe for people with allergies thanks to a formula completely free from nuts and nut derivatives
No Colorants
Every shade comes from nature with no synthetic colorants or coatings added
No Pesticides
All raw materials are carefully tested and guaranteed to be residue free and pure.
Real stories that inspire
Discover the inspiring success stories of those who’ve experienced real results.
Yesterday you said tomorrow. Today you start.
CHF 2.00/portion with 12-month subscription
First purchase includes:
ONE Welcome Box
A beautifully designed unboxing experience
FREE
CHF 10.00ONE Signature Bottle
Show that you’re part of our community
FREE
CHF 18.00